Saturday, December 12, 2009

Grow Bone, Gingivitis in Your genes, Gum disease vaccine, Man vs Women

Diastema Closure with Composite
Patients present to the office with spaces between their teeth that they would like to have closed on a regular basis. There are numerous ways to treat these patients, which may include orthodontics, periodontics, and restorative dentistry. Often times, the treatment proposed is based on the comfort level or skill of the providing dentist. Porcelain veneers are often the treatment modality chosen because of the predictability and financial reward.

Composite resins, on the other hand, require a higher skill level by dentists because they are fabricating the restoration instead of the ceramist. The advent of newer composite resins, which give us added strength and polishability, provides us new modalities with which to satisfy patients' expectations. FULL PAPER



 Dental Stem Cells Regrow Bone
StemSave,Inc., the market leader in the field of stem cell recovery and cryo-preservation lauds research published in the November issue of the European Cells and Materials Journal citing the reconstruction of the human mandible bone with autologous dental pulp stem cells. StemSave commends Italian researchers from the 2nd University of Naples for their groundbreaking work.

This marks the first time dental stem cell research has moved from the laboratory to human clinical trials. The repair and regeneration of bone is particularly significant for the oral maxillofacial field because the repair of these bones, which aid in orofacial functions like speech, chewing, swallowing and facial expressions are extremely intricate and complex. MORE HERE

Men lose their minds speaking to pretty women


The research shows men who spend even a few minutes in the company of an attractive woman perform less well in tests designed to measure brain function than those who chat to someone they do not find attractive.

Researchers who carried out the study, published in the Journal of Experimental and Social Psychology, think the reason may be that men use up so much of their brain function or 'cognitive resources' trying to impress beautiful women, they have little left for other tasks.
Women, however, were not affected by chatting to a handsome man. MORE HERE 

And Now a Vaccine for Gum disease, How Soon ?
Australian scientists are leading a push to produce a vaccine to treat severe gum disease. Up to one third of the population suffers from it and the condition has also been linked to heart disease and even strokes.

The vaccine's developers say they hope to prevent the disease progressing. That's in contrast to existing treatments which only manage the symptoms. The whole notion is to make a vaccine that would treat colonisation of people's mouths with porphyromonas gingivalis and thereby slow or halt the progress of the periodontal disease and thereby save people's teeth. MORE HERE

Old Silver Fillings are not Toxic
Using a special X-ray technique, the scientists analyzed the surface of freshly prepared metal fillings and compared these with the surface of aged fillings (about 20 years old) from a dental clinic. Fresh fillings contained metallic mercury, which can be toxic. Aged fillings, however, typically contain a form of mercury, called beta-mercuric sulfide or metacinnabar, which is unlikely to be toxic in the body. Full REPORT

Nearly One Third of Human Genome Is Involved in Gingivitis
Gingivitis, which may affect more than one-half of the U.S. adult population, is a condition commonly attributed to lapses in simple oral hygiene habits. However, a new study shows that development and reversal of gingivitis at the molecular level is apparently much more complicated than its causes might indicate.
Research conducted jointly by the University of North Carolina at Chapel Hill and Procter & Gamble (P&G) Oral Care has found that more than 9,000 genes -- nearly 30 percent of the genes found in the human body are expressed differently during the onset and healing process associated with gingivitis.
Results of the study are published today in the December 2009 edition of the Journal of Periodontology. This study is the first to successfully identify gene expression and biological pathways involved with the onset and healing process of gingivitis. MORE HERE

Protective role of osteopontin in endodontic infection
Immunology-Volume 129 Issue 1, Pages 105 - 114
Endodontic infections are polymicrobial infections resulting in bone destruction and tooth loss. The host response to these infections is complex, including both innate and adaptive mechanisms. Osteopontin (OPN), a secreted, integrin-binding protein, functions in the regulation of immune responses and enhancement of leucocyte migration.
This study assessed the role of OPN in the host response to endodontic infection using a well-characterized mouse model.
Study concluded that OPN has a protective effect on polymicrobial infection, at least partially because of alterations in phagocyte recruitment and/or persistence at the sites of infection, and that this molecule has a potential therapeutic role in polymicrobial infections.

Paper Point technique for WL in Endodontics
Triple O, Volume 108, Issue 5, Pages e101-e105 (November 2009)
Despite not having been formally evaluated in the endodontic literature, claims have been made regarding the acceptability of the paper point technique (PPT) in estimating the location of the apical foramen (AF). Our aim was to investigate the repeatability and accuracy of PPT in estimating AF location in a cohort of dental patients.

Root canals with ≤10° of curvature (n = 71) in unsalvageable anterior and premolar teeth were measured using PPT as described in the literature. An endodontic file was cemented in each canal to the position indicated by PPT. Teeth were extracted and microscopic computerized tomography scanned.
The PPT was 0.5 mm short to 0.5 mm long of AF in 87% of the canals. Repeated measurements in a given canal were within 0.19 mm of each other 95% of the time.

For relatively straight root canals, PPT appears to be similar to current clinically acceptable, NOTE- It is a well known fact that most canals are curved even though they appear straight in radiograph.

New Mouthwash will give long term Caries protection
A research team at the University of Nebraska Medical Center has developed a new mouthwash formulation that may provide long-term protection against tooth decay. “The beauty of this design is the simplicity. All one may have to do is their routine oral hygiene procedure and then rinse with the formulation that we have developed. It could protect the teeth over a long period of time,” Dr. Wang said. “The key is to have the antimicrobials stay where they are most needed – the tooth surface.” MORE HERE

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