Secret OF Success and Happiness
Wisdom Teeth As Source Of Stem Cells
Researchers in Japan have successfully made stem cells from wisdom teeth, creating an alternative source of pluripotent cells for researching and treating disease and avoiding the ethical problems surrounding the use of embryonic stem cells.
Scientists at Japan's National Institute of Advanced Industrial Science and Technology, which is funded by the government, said they used wisdom teeth that had been frozen for three years after being removed from a 10 year old girl. Lead investigator of the project, Hajime Ogushi, told AFP news agency that their work was significant for two reasons. First, it avoids the ethical problem of using embryonic stem cells, and besides, wisdom teeth are usually thrown away, and second, it is easy to stock wisdom teeth.
Ogushi and colleagues extracted cells from the donated wisdom teeth, inserted three of the genes used by Yamanaka's team, and cultured the cells for just over a month in the lab. When they tested the cells they found them to be stem cells, Ogushi told AFP.
One application would be to use the cells to treat inherited bone disease, but Ogushi explained it will take at least 5 years of development and trials before the idea even gets into the clinical setting.
As to harvesting stem cells from wisdom teeth, Ogushi said there would be no problem with supply, since extraction of wisdom teeth is quite a common dental procedure. Having such a plentiful source of donors means scientists could produce stem cells with a range of genetic codes, increasing the chance that a patient's immune system will not reject the transplanted tissue or organ.
Another application could be that people who have their wisdom teeth out could arrange for them to be stored for future use as a source of stem cells already tailored to their own genetic code.
Change Lifestyle, Change Genes, june 2008
You can't get different genes, but how you act, can change how your genes function, report Dean Ornish, M.D., and colleagues at the University of California, San Francisco (UCSF).
Ornish is a clinical professor of medicine at UCSF and also a diet guru who's been telling us for years that by improving our lifestyle we can prevent and even reverse many chronic diseases. And Ornish has been putting his money where his mouth is, backing a number of scientific studies that support his arguments.
Now, in a new kind of study, Ornish is joined by UCSF professor and chairman of urology Peter Carroll, M.D.; UCSF prostate-cancer geneticist Christopher Haqq, MD, PhD; and others. The goal of this pilot study was to see whether the Ornish lifestyle could help 30 men with low-risk prostate cancer who chose not to undergo treatment unless their cancer got worse.
It's too soon to say whether the men's lifestyle changes kept their cancer at bay. But genetic analysis revealed profound differences in noncancerous prostate tissues in just three months.
More than 500 genes changed the way they worked. Genes with beneficial effects, including some tumor-suppression genes, became more active. Genes with deleterious effects, including some cancer-promoting genes, were switched off. Full Story HERE
To know what is Ornish Diet click here, It can reverse your heart blockage as well. There is also Dr Vimal Chajeda in India who conducts regular workshops and thousands have escaped bypass surgeries by following his advice.
If you are looking for the eternal secret of happiness CLICK HERE
Looking for success in life, follow the attractor principle and attract whatever you want in life, also read the excellent book "Beyond positive thinking" for details email icdr@hotmail.com
Clinical and microbiological benefits of systemic metronidazole and amoxicillin in the treatment of smokers with chronic periodontitis: a randomized placebo-controlled study- published in J of Cli Perio Aug 2008
Aim: The aim of this study was to evaluate the clinical and microbiological effects of scaling and root planing (SRP) alone or combined with metronidazole (MTZ) or with MTZ and amoxicillin (AMX) in the treatment of smokers with chronic periodontitis.
Methods: A double-blind, placebo-controlled, randomized clinical trial was conducted in 43 subjects who received SRP alone (n=15) or combined with MTZ (400 mg 3 × per day, n=14) or with MTZ+AMX (500 mg 3 × per day, n=14) for 14 days. Clinical and microbiological examinations were performed at baseline and 3 months post-therapy. Subgingival samples were analysed by checkerboard DNA–DNA hybridization.
Results: Subjects receiving MTZ+AMX showed the greatest improvements in mean probing depth and clinical attachment level. Both antibiotic therapies led to additional clinical benefits over SRP alone in initially shallow, intermediate, and deep sites. The SRP+MTZ+AMX therapy led to the most beneficial changes in the subgingival microbial profile. These subjects showed significant reductions in the mean counts and proportions of periodontal pathogens such as Tannerella forsythia, Porphyromonas gingivalis and Treponema denticola, and the greatest increase in proportions of host-compatible species.
Conclusion: Significant advantages are observed when systemic antibiotics are combined with SRP in the treatment of smokers with chronic periodontitis. The greatest benefits in clinical and microbiological parameters are achieved with the use of SRP+MTZ+AMX.
Researchers in Japan have successfully made stem cells from wisdom teeth, creating an alternative source of pluripotent cells for researching and treating disease and avoiding the ethical problems surrounding the use of embryonic stem cells.
Scientists at Japan's National Institute of Advanced Industrial Science and Technology, which is funded by the government, said they used wisdom teeth that had been frozen for three years after being removed from a 10 year old girl. Lead investigator of the project, Hajime Ogushi, told AFP news agency that their work was significant for two reasons. First, it avoids the ethical problem of using embryonic stem cells, and besides, wisdom teeth are usually thrown away, and second, it is easy to stock wisdom teeth.
Ogushi and colleagues extracted cells from the donated wisdom teeth, inserted three of the genes used by Yamanaka's team, and cultured the cells for just over a month in the lab. When they tested the cells they found them to be stem cells, Ogushi told AFP.
One application would be to use the cells to treat inherited bone disease, but Ogushi explained it will take at least 5 years of development and trials before the idea even gets into the clinical setting.
As to harvesting stem cells from wisdom teeth, Ogushi said there would be no problem with supply, since extraction of wisdom teeth is quite a common dental procedure. Having such a plentiful source of donors means scientists could produce stem cells with a range of genetic codes, increasing the chance that a patient's immune system will not reject the transplanted tissue or organ.
Another application could be that people who have their wisdom teeth out could arrange for them to be stored for future use as a source of stem cells already tailored to their own genetic code.
Change Lifestyle, Change Genes, june 2008
You can't get different genes, but how you act, can change how your genes function, report Dean Ornish, M.D., and colleagues at the University of California, San Francisco (UCSF).
Ornish is a clinical professor of medicine at UCSF and also a diet guru who's been telling us for years that by improving our lifestyle we can prevent and even reverse many chronic diseases. And Ornish has been putting his money where his mouth is, backing a number of scientific studies that support his arguments.
Now, in a new kind of study, Ornish is joined by UCSF professor and chairman of urology Peter Carroll, M.D.; UCSF prostate-cancer geneticist Christopher Haqq, MD, PhD; and others. The goal of this pilot study was to see whether the Ornish lifestyle could help 30 men with low-risk prostate cancer who chose not to undergo treatment unless their cancer got worse.
It's too soon to say whether the men's lifestyle changes kept their cancer at bay. But genetic analysis revealed profound differences in noncancerous prostate tissues in just three months.
More than 500 genes changed the way they worked. Genes with beneficial effects, including some tumor-suppression genes, became more active. Genes with deleterious effects, including some cancer-promoting genes, were switched off. Full Story HERE
To know what is Ornish Diet click here, It can reverse your heart blockage as well. There is also Dr Vimal Chajeda in India who conducts regular workshops and thousands have escaped bypass surgeries by following his advice.
If you are looking for the eternal secret of happiness CLICK HERE
Looking for success in life, follow the attractor principle and attract whatever you want in life, also read the excellent book "Beyond positive thinking" for details email icdr@hotmail.com
Clinical and microbiological benefits of systemic metronidazole and amoxicillin in the treatment of smokers with chronic periodontitis: a randomized placebo-controlled study- published in J of Cli Perio Aug 2008
Aim: The aim of this study was to evaluate the clinical and microbiological effects of scaling and root planing (SRP) alone or combined with metronidazole (MTZ) or with MTZ and amoxicillin (AMX) in the treatment of smokers with chronic periodontitis.
Methods: A double-blind, placebo-controlled, randomized clinical trial was conducted in 43 subjects who received SRP alone (n=15) or combined with MTZ (400 mg 3 × per day, n=14) or with MTZ+AMX (500 mg 3 × per day, n=14) for 14 days. Clinical and microbiological examinations were performed at baseline and 3 months post-therapy. Subgingival samples were analysed by checkerboard DNA–DNA hybridization.
Results: Subjects receiving MTZ+AMX showed the greatest improvements in mean probing depth and clinical attachment level. Both antibiotic therapies led to additional clinical benefits over SRP alone in initially shallow, intermediate, and deep sites. The SRP+MTZ+AMX therapy led to the most beneficial changes in the subgingival microbial profile. These subjects showed significant reductions in the mean counts and proportions of periodontal pathogens such as Tannerella forsythia, Porphyromonas gingivalis and Treponema denticola, and the greatest increase in proportions of host-compatible species.
Conclusion: Significant advantages are observed when systemic antibiotics are combined with SRP in the treatment of smokers with chronic periodontitis. The greatest benefits in clinical and microbiological parameters are achieved with the use of SRP+MTZ+AMX.
posted by Healthmantra at
7:47 PM
0 Comments:
Post a Comment
<< Home