Your Curing Light can Stunt Tumor Growth, Regrowing Pulp in Young Teeth
Regrowing Pulp in Young Teeth -Journal of Endodontics July 2008
Although contemporary nonsurgical endodontic procedures confer high degrees of clinical success , the root canal system is obturated with synthetic materials, preventing any of the advantages that might ensue by regeneration of a functional pulp-dentin complex. This is a particular problem when treating the necrotic but immature permanent tooth, where conventional treatment often leads to resolution of apical periodontitis, but the tooth remains susceptible to fracture as a result of interruption of apical and dentinal wall development. Thus, one alternative approach would be to develop and validate biologically based endodontic procedures designed to restore a functional pulp-dentin complex.
For more than 50 years, clinicians have evaluated biologically based methods to restore a functional pulp-dentin complex in teeth with necrotic root canal systems caused primarily by trauma or caries. Although case series from the 1960s–1970s in general were not successful in producing this outcome , it should be appreciated that they were performed without contemporary instruments or materials and without insight generated from the trauma or tissue engineering fields. More recent case reports, published during the last 15 years, have demonstrated that it is possible in humans to restore a functional pulp-dentin complex in the necrotic immature permanent tooth. Full paper here
Blue Light Used To Harden Tooth Fillings Stunts Tumor Growth
ScienceDaily (June 24, 2008) — A blue curing light used to harden dental fillings also may stunt tumor growth, Medical College of Georgia researchers say. "The light sends wavelengths of blue-violet light to the composite, which triggers hardening," says Alpesh Patel, a rising MCG School of Dentistry junior. "The light waves produce free radicals that activate the catalyst and speed up polymerization of the composite resin.
In oral cancer cells, though, those radicals cause damage that decreases cell growth and increases cell death." Mr. Patel, who has been working with Dr. Jill Lewis, associate professor of oral biology, Dr. Regina Messer, associate professor of oral rehabilitation and oral biology, and Dr. John Wataha, adjunct professor of oral rehabilitation and oral biology, studied 10 tumor-bearing mice, five treated with the light and five untreated. He exposed half the mice to the blue light for 90 seconds a day for 12 days. Then the tumors were extracted and each one was split into two sections. Half were used to create slides for tissue analysis, and half were frozen to prepare protein extracts.
Tissue analysis indicated an approximate 10 percent increase in cell suicide, or apoptosis, in the light-treated tumors. The frozen protein extracts revealed a nearly 80 percent decrease in cell growth in the light-treated tumors. "The decrease in cell growth, combined with increased apoptosis, helps explain why the tumors didn't grow as much because you have cells that aren't dividing and you have cells that are committing suicide," Mr. Patel says. More HERE
Australia Patient pulls his own tooth, June 25, 2008
A NSW man who has been on the dental waiting list since 2004 was in such excruciating pain that he took the extreme measure of pulling out one of his teeth.
For four years, Jeffrey Miners has survived on a daily cocktail of painkillers but four weeks ago, his excruciating gum pain was no longer bearable and he pulled out the tooth.
The 58-year-old, who has other complex health problems, has been on the NSW dental waiting list since 2004 and still has no date for his surgery despite urgently needing 13 teeth extracted.
Mr Miners said he also had to take painkillers, which made him feel "like a zombie", to deal with the pain from his damaged mouth and inflamed gums.
"And every day and night I'm waking up and I'm just sucking poison, and there are putrid smells. It is sickening," he said.
"I've had one filling done in a tooth, back in 2005, and that's in a seven-year wait."
Opposition health spokeswoman Jillian Skinner said it was outrageous that almost 160,000 people were still waiting for necessary dental treatment in NSW.
"Patients like Jeffrey Miners are waiting in pain and undertaking drastic action because Health Minister Reba Meagher has failed to give them appropriate dental care," Mrs Skinner said.
More about dentistry in Australia
Teeth And Jewelry Don't Mix
ScienceDaily (June 24, 2008) — Skin piercings might be the rage among teens, but researchers from Tel Aviv University have found good reasons to think twice about piercing one’s tongue or lip.
Dr. Liran Levin, a dentist from the Department of Oral Rehabilitation, School of Dental Medicine at Tel Aviv University has found that about 15 to 20 percent of teens with oral piercings are at high risk for both tooth fractures and gum disease. Resulting tooth fractures as well as periodontal problems, he says, can lead to anterior (front) tooth loss later in life.
High rates of fractures due to piercings are not found in other age groups, and cases of severe periodontal damage in teens without oral piercings are similarly rare, says Dr. Levin, who conducted the study with partners Dr. Yehuda Zadik and Dr. Tal Becker, both dentists in the Israeli Army.
Their initial study was done on 400 young adults aged 18-19, and the results were published in the well-known peer-reviewed journal Dental Traumatology in 2005. A new review by Drs. Levin and Zadik published in the American Dental Journal in late 2007 is the first and largest of its kind to document the risks and complications of oral piercings, drawing on research from multiple centers in America and across the world. More HERE
Although contemporary nonsurgical endodontic procedures confer high degrees of clinical success , the root canal system is obturated with synthetic materials, preventing any of the advantages that might ensue by regeneration of a functional pulp-dentin complex. This is a particular problem when treating the necrotic but immature permanent tooth, where conventional treatment often leads to resolution of apical periodontitis, but the tooth remains susceptible to fracture as a result of interruption of apical and dentinal wall development. Thus, one alternative approach would be to develop and validate biologically based endodontic procedures designed to restore a functional pulp-dentin complex.
For more than 50 years, clinicians have evaluated biologically based methods to restore a functional pulp-dentin complex in teeth with necrotic root canal systems caused primarily by trauma or caries. Although case series from the 1960s–1970s in general were not successful in producing this outcome , it should be appreciated that they were performed without contemporary instruments or materials and without insight generated from the trauma or tissue engineering fields. More recent case reports, published during the last 15 years, have demonstrated that it is possible in humans to restore a functional pulp-dentin complex in the necrotic immature permanent tooth. Full paper here
Blue Light Used To Harden Tooth Fillings Stunts Tumor Growth
ScienceDaily (June 24, 2008) — A blue curing light used to harden dental fillings also may stunt tumor growth, Medical College of Georgia researchers say. "The light sends wavelengths of blue-violet light to the composite, which triggers hardening," says Alpesh Patel, a rising MCG School of Dentistry junior. "The light waves produce free radicals that activate the catalyst and speed up polymerization of the composite resin.
In oral cancer cells, though, those radicals cause damage that decreases cell growth and increases cell death." Mr. Patel, who has been working with Dr. Jill Lewis, associate professor of oral biology, Dr. Regina Messer, associate professor of oral rehabilitation and oral biology, and Dr. John Wataha, adjunct professor of oral rehabilitation and oral biology, studied 10 tumor-bearing mice, five treated with the light and five untreated. He exposed half the mice to the blue light for 90 seconds a day for 12 days. Then the tumors were extracted and each one was split into two sections. Half were used to create slides for tissue analysis, and half were frozen to prepare protein extracts.
Tissue analysis indicated an approximate 10 percent increase in cell suicide, or apoptosis, in the light-treated tumors. The frozen protein extracts revealed a nearly 80 percent decrease in cell growth in the light-treated tumors. "The decrease in cell growth, combined with increased apoptosis, helps explain why the tumors didn't grow as much because you have cells that aren't dividing and you have cells that are committing suicide," Mr. Patel says. More HERE
Australia Patient pulls his own tooth, June 25, 2008
A NSW man who has been on the dental waiting list since 2004 was in such excruciating pain that he took the extreme measure of pulling out one of his teeth.
For four years, Jeffrey Miners has survived on a daily cocktail of painkillers but four weeks ago, his excruciating gum pain was no longer bearable and he pulled out the tooth.
The 58-year-old, who has other complex health problems, has been on the NSW dental waiting list since 2004 and still has no date for his surgery despite urgently needing 13 teeth extracted.
Mr Miners said he also had to take painkillers, which made him feel "like a zombie", to deal with the pain from his damaged mouth and inflamed gums.
"And every day and night I'm waking up and I'm just sucking poison, and there are putrid smells. It is sickening," he said.
"I've had one filling done in a tooth, back in 2005, and that's in a seven-year wait."
Opposition health spokeswoman Jillian Skinner said it was outrageous that almost 160,000 people were still waiting for necessary dental treatment in NSW.
"Patients like Jeffrey Miners are waiting in pain and undertaking drastic action because Health Minister Reba Meagher has failed to give them appropriate dental care," Mrs Skinner said.
More about dentistry in Australia
Teeth And Jewelry Don't Mix
ScienceDaily (June 24, 2008) — Skin piercings might be the rage among teens, but researchers from Tel Aviv University have found good reasons to think twice about piercing one’s tongue or lip.
Dr. Liran Levin, a dentist from the Department of Oral Rehabilitation, School of Dental Medicine at Tel Aviv University has found that about 15 to 20 percent of teens with oral piercings are at high risk for both tooth fractures and gum disease. Resulting tooth fractures as well as periodontal problems, he says, can lead to anterior (front) tooth loss later in life.
High rates of fractures due to piercings are not found in other age groups, and cases of severe periodontal damage in teens without oral piercings are similarly rare, says Dr. Levin, who conducted the study with partners Dr. Yehuda Zadik and Dr. Tal Becker, both dentists in the Israeli Army.
Their initial study was done on 400 young adults aged 18-19, and the results were published in the well-known peer-reviewed journal Dental Traumatology in 2005. A new review by Drs. Levin and Zadik published in the American Dental Journal in late 2007 is the first and largest of its kind to document the risks and complications of oral piercings, drawing on research from multiple centers in America and across the world. More HERE
posted by Healthmantra at
9:10 AM
0 Comments:
Post a Comment
<< Home